From glass to medicine — integrated manufacturing strength.
From glass to medicine — integrated manufacturing strength.
Mefar Manufacturing Facility
Mefar İlaç Sanayii A.Ş., with more than 40 years of experience in sterile parenteral and ophthalmic products and over 15 years of experience in human inactivated vaccine manufacturing, provides high-quality contract manufacturing services to local and international partners at its modern manufacturing facility in Kurtköy, Istanbul. Operating in compliance with current Turkish and European Union GMP requirements, the facility combines advanced manufacturing technologies with an experienced team to deliver high-quality production.
Located on a total area of approximately 32,000 m², the facility has 28,411 m² of indoor space. Its strategic location close to the TEM and Northern Marmara Motorway connections and Sabiha Gökçen International Airport provides significant advantages for both domestic and international logistics operations.
Sterile Manufacturing Capabilities
Mefar’s sterile manufacturing infrastructure is designed to support production in ampoule, vial, pre-filled syringe (PFS), cartridge and BFS (Blow-Fill-Seal) formats.
The facility supports both liquid filling and lyophilized product manufacturing. Fully automated filling lines accommodate glass or polypropylene syringe and cartridge formats, serving a broad range of production requirements from high-volume commercial projects to flexible, lower-volume manufacturing needs. BFS technology enables a variety of sterile filling solutions, ranging from single-use nebules and strips to multi-use bottle formats.
Secondary packaging, QR code printing and serialization services are also provided for domestic and export markets.
The Mefar Manufacturing Facility is regularly inspected by the Turkish Ministry of Health, EMA, EAEU and other health authorities in accordance with current GMP requirements. The facility holds GMP certificates issued by TİTCK and various European and international health authorities and operates in accordance with ISO 9001 and ISO 13485 quality standards.
All stages of manufacturing are supported by 24/7 camera monitoring systems, comprehensive Quality Assurance processes, and chemical and microbiological control laboratories. This helps ensure product compliance with registered specifications and consistent quality.
In addition to its manufacturing services, Mefar provides comprehensive support to its customers through its R&D Center, serving as a reliable product and process development partner for formulations across different therapeutic areas.
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million units annual Ampoule filling
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million units annual vial filling
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million units annual PFS filling
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million units annual BFS filling
Birgi Manufacturing Facility
With more than 60 years of industry experience, Birgi Sanayi A.Ş. is a leading manufacturing facility specializing in primary glass packaging for the pharmaceutical and cosmetics industries. Located in Samandıra, Istanbul, the facility serves local and international customers with its modern manufacturing infrastructure and high quality standards.
Operating across 7,750 m² of indoor and 1,000 m² of outdoor space, the facility benefits from its proximity to the TEM and Northern Marmara Motorway connections and Sabiha Gökçen International Airport, enabling efficient and fast logistics solutions.
Primary Glass Packaging Manufacturing Capabilities
At the Birgi Manufacturing Facility, Type I glass ampoules in volumes ranging from 1–30 mL and Type I glass vials ranging from 2–30 mL are manufactured to meet the diverse needs of the pharmaceutical industry. Manufacturing processes are carried out in accordance with ISO, DIN and relevant international standards.
A range of customization options is available according to customer requirements, including screen/ceramic printing, break rings, OPC (One Point Cut) and identification rings.
Vials manufactured by Birgi have Drug Master File (DMF) registrations with the U.S. Food and Drug Administration (FDA) and Health Canada.
The facility operates in accordance with ISO 9001 and ISO 15378 quality standards. Production areas are monitored 24/7, while dimensional and cosmetic inspections are performed using 100% camera inspection systems.
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Millon units annual ampoule production
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Million units annual vial production